MetaVital™ Human Glutathione S Transferase Mu 2, Muscle (GSTm2) ELISA Kit

CAT#: ITS-0326-WB55
Product Type: ELISA Kit
Species: Human
Target: Human Glutathione S Transferase Mu 2, Muscle (GSTm2) protein
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantitatively measures GSTm2 concentrations in human muscle tissues and biological fluids with high specificity.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Human GSTm2 ELISA Kit enables precise in vitro quantification of Glutathione S Transferase Mu 2 in tissue homogenates, cell lysates, and various biological fluids, supporting translational and clinical research.
Features
Sandwich ELISA format ensures high specificity and reproducibility for accurate GSTm2 detection across diverse human samples.
Sensitive detection range from 0.78 to 50 ng/mL with a 0.47 ng/mL limit, capturing low-abundance proteins.
Includes pre-coated 96-well plates, lyophilized standards, and optimized reagents for streamlined workflow and consistency.
Colorimetric detection with TMB substrate provides reliable, quantitative measurement suitable for high-throughput studies.
Process Relevance
Supports monitoring GSTm2 levels to investigate muscle detoxification and oxidative stress responses in human tissues.
Application Stage
Applicable in biomarker validation, disease research, and clinical translational studies.
Applications
Ideal for quantitative ELISA assays, analyzing tissue homogenates, cell lysates, and biological fluids for GSTm2 concentration, enzyme activity, ADME profiling studies, and pathway studies.
Target
Human Glutathione S Transferase Mu 2, Muscle (GSTm2) protein
Detection Method
Colorimetric
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Muscle physiology, pharmacokinetics (ADME), oxidative stress research, pharmacology, biomarker discovery, enzymology, clinical diagnostics, toxicology, etc.
Size
96 tests
Data Output Type
Quantitative protein concentration measurement using colorimetric ELISA readouts.
Assay Range
0.78 ng/ml - 50 ng/ml
LOD
0.47 ng/ml
Species
Human
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Glutathione S Transferase Mu 2 (GSTm2) is a detoxifying enzyme that conjugates reduced glutathione to reactive intermediates, protecting muscle tissues from oxidative damage and xenobiotic toxicity. Its expression reflects metabolic stress and pharmacological responses in skeletal muscle.
Pathways
GSTm2 participates in phase II detoxification, glutathione metabolism, and oxidative stress defense. Upstream modulators include reactive oxygen species, while downstream effects involve reduced cellular toxicity and maintenance of redox homeostasis.
For Research Use Only | Not For Clinical Use
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