MetaVital™ Rat Flavin Containing Monooxygenase 5 (FMO5) ELISA Kit

CAT#: ITS-0326-WB17
Product Type: ELISA Kit
Species: Rat
Target: Rat Flavin Containing Monooxygenase 5 (FMO5) enzyme
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantitatively measures FMO5 concentrations in rat tissue, cell lysates, and biological fluids using ELISA.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Rat FMO5 ELISA Kit provides a precise in vitro solution for detecting and quantifying Flavin Containing Monooxygenase 5 in rat samples. It supports research in xenobiotic metabolism, drug biotransformation, and tissue-specific enzyme activity with high sensitivity and reproducibility.
Features
High specificity ELISA designed for rat FMO5, enabling accurate quantification in diverse biological samples, including tissues and cell lysates.
Sensitive colorimetric detection covering 0.156-10 ng/mL, providing reliable measurements across low- and mid-range concentrations.
Lyophilized standard included ensures stability and consistent assay performance over a six-month shelf life.
User-friendly format allows efficient processing of up to 96 tests per kit with minimal variability between runs.
Process Relevance
Enables precise monitoring of FMO5 to assess enzyme regulation, xenobiotic metabolism, and tissue-specific expression in rat models.
Application Stage
Suitable for preclinical drug metabolism studies, toxicology research, and in vitro biochemical analysis.
Applications
Quantitative ELISA measurement of FMO5 in tissue homogenates, cell lysates, or other biological fluids for metabolic, pharmacological, ADME profiling studies, and toxicological studies.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Target
Rat Flavin Containing Monooxygenase 5 (FMO5) enzyme
Detection Method
Colorimetric
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Drug metabolism, toxicology, pharmacokinetics (ADME), hepatic enzyme regulation, preclinical pharmacology, etc.
Size
96 tests
Data Output Type
Quantitative measurement of FMO5 concentrations using colorimetric detection (endpoint).
Assay Range
0.156 ng/ml - 10 ng/ml
Species
Rat
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Flavin containing monooxygenase 5 (FMO5) is a liver-enriched enzyme involved in the oxidative metabolism of drugs and xenobiotics. Its activity influences pharmacokinetic profiles, chemical detoxification, and tissue-specific metabolic pathways in preclinical rat models.
Pathways
FMO5 participates in the oxidative N-oxygenation of nucleophilic xenobiotics and endogenous compounds. It operates downstream of substrate uptake, contributing to drug metabolism and hepatic detoxification, and interfaces with phase II conjugation pathways.
For Research Use Only | Not For Clinical Use
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