Methylmalonyl CoA Epimerase-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR17
Cell Type: CD8 T Cells
RNA writers: NSUN5
RNA readers: YTHDF2
RNA erasers: TET1/2/3
Enzymes: SIRT1
RNA types: tRNA
Modification: ψ
RNA editing: C to U
Short Description
This product is a Methylmalonyl CoA epimerase-targeted RNA modification and metabolomics analysis tool based on the ψ (NSUN5-YTHDF2-TET1/2/3-SIRT1-DBCO) modification and Mevalonate pathway-mediated (RBFOX1-Acetyl-CoA-ATP) metabolic analysis system.
RNA writers
NSUN5
RNA readers
YTHDF2
RNA erasers
TET1/2/3
Enzymes
SIRT1
RNA types
tRNA
Modification
ψ
Label
DBCO
RNA editing
C to U
Cell Type
CD8 T Cells
Oligonucleotide
PS, 2'-OMe, 2'-F, GalNAc
RNA Construction
tRNA-ψ-NSUN5-YTHDF2-TET1/2/3-SIRT1-DBCO
Substrates
Acetyl-CoA
Cofactors
ATP
Pathway
Mevalonate pathway
Epigenetic regulator
SIRT6 deficiency
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
RBFOX1
Metabolic Reprogramming
Mevalonate pathway-RBFOX1-Acetyl-CoA-ATP
Target
Methylmalonyl CoA epimerase
Alternative Names
Methylmalonyl CoA epimerase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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