ModifiSite™ Aldehyde Dehydrogenase Assay Kit

CAT#: ITS-1125-HM8
Product Type: Assay Kit
Species: All Species
Brand: ModifiSite
Development Stage: Research-Grade Protein & Enzyme Assay Development
Short Description
Determines ALDH enzyme activity, crucial for alcohol metabolism.
Brand
ModifiSite
Development Stage
Research-Grade Protein & Enzyme Assay Development
Description
The ModifiSite™ Aldehyde Dehydrogenase Assay Kit validates the activity of critical detoxification enzymes, which is essential for developing therapies for alcohol dependence and oxidative stress disorders. By quantifying ALDH activity, researchers can assess the efficacy of drugs designed to mitigate aldehyde-induced cellular damage. This robust protocol is suitable for automated systems, facilitating high-throughput screening of compounds that modulate detoxification pathways.
Features
Fast and robust protocol suitable for automated systems; Validates ALDH activity modulation in oxidative stress and addiction therapy research.
Process Relevance
Oxidative Stress & Detoxification
Application Stage
ADME / DMPK
Applications
Investigates oxidative stress responses and alcohol metabolism pathways.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 565 nm
Sample Type
Serum, citrate-plasma, urine, cell lysate, culture medium
Research Areas
Toxicology; Oxidative Stress
Size
100 tests
Data Output Type
Kinetic (Enzyme Activity)
Assay Time
Results in 30min
LOD
0.2 U/L
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Aldehyde Dehydrogenases (ALDH) are a family of enzymes that detoxify endogenous and exogenous aldehydes by oxidizing them to carboxylic acids. ALDH activity is crucial for alcohol metabolism and protecting cells from oxidative stress induced by lipid peroxidation.
For Research Use Only | Not For Clinical Use
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