Short Description
Enzymatic determination of alpha-amylase activity.
Development Stage
Research-Grade Protein & Enzyme Assay Development
Description
The ModifiSite™ α-Amylase Assay Kit utilizes a specific substrate to validate the efficacy of starch blockers and anti-diabetic compounds targeting post-prandial glucose excursions. This kinetic assay supports the evaluation of pancreatic function and carbohydrate digestion in metabolic disease models. By quantifying amylase inhibition, it aids in the development of nutritional and pharmacological interventions for glycemic control.
Features
Colorimetric kinetic assay; Validates starch blockers and anti-diabetic compounds targeting post-prandial glucose.
Process Relevance
Metabolic Disease Drug Screening
Application Stage
Hit-to-Lead Screening
Applications
Pancreatic function testing and starch hydrolysis studies.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 405 nm
Sample Type
Serum, citrate-plasma, urine, cell lysate, culture medium
Research Areas
Gastroenterology; Diabetes & Obesity
Datasheet