Short Description
Measures Glyoxalase I activity.
Development Stage
Research-Grade Protein & Enzyme Assay Development
Description
The ModifiSite™ Glyoxalase I Assay Kit employs a UV kinetic measurement to validate the detoxification of methylglyoxal, relevant in diabetes and aging research. This assay measures the first step in the glyoxalase system, protecting cells from glycative stress. It supports the investigation of advanced glycation end-product (AGE) formation and metabolic defense mechanisms.
Features
UV kinetic measurement; Validates detoxification of methylglyoxal in diabetes and aging research.
Process Relevance
Aging & Diabetes Research
Application Stage
Basic Research
Applications
Methylglyoxal detoxification and diabetes research.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 240 nm (Use a UV plate, e.g. 96-well UV plate, cat# P96UV)
Sample Type
Enzyme preparations or biological samples
Research Areas
Diabetes; Aging Research
Datasheet