Development Stage: Research-Grade Protein & Enzyme Assay Development
Short Description
Determines MPO activity, a marker of inflammation.
Brand
ModifiSite
Development Stage
Research-Grade Protein & Enzyme Assay Development
Description
The ModifiSite™ Myeloperoxidase Assay Kit measures peroxidation activity, serving as a biomarker for neutrophil infiltration and inflammation in tissues. This assay validates anti-inflammatory drugs by quantifying the accumulation of MPO in affected organs. It supports research into vasculitis, atherosclerosis, and other inflammatory conditions.
Features
Peroxidation activity measurement; Biomarker for neutrophil infiltration and inflammation in tissues.
Process Relevance
Inflammation Biomarker Quantification
Application Stage
Pre-clinical Efficacy
Applications
Neutrophil activation and inflammation quantification.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Fluorescence Detection (Ex 530 nm / Em 585 nm)
Sample Type
Cell lysates, tissues, samples
Research Areas
Inflammation; Cardiovascular Disease
Size
100 tests
Data Output Type
Kinetic (Enzyme Activity)
Assay Time
Results in 30 min
LOD
0.0025 U/L
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Myeloperoxidase (MPO) is abundant in neutrophils producing hypohalous acids to kill pathogens. It also contributes to tissue damage in chronic inflammation and serves as a cardiovascular risk marker.