Development Stage: Research-Grade Protein & Enzyme Assay Development
Short Description
Quantifies neuraminidase (sialidase) activity.
Brand
ModifiSite
Development Stage
Research-Grade Protein & Enzyme Assay Development
Description
The ModifiSite™ Neuraminidase Assay Kit features a fluorometric substrate for the high-throughput screening of neuraminidase inhibitors, essential for influenza therapeutics. This assay validates the potency of antiviral drugs that block viral release from host cells. It supports virology research and the monitoring of drug resistance in influenza strains.
Features
Fluorometric substrate; High-throughput screening of neuraminidase inhibitors for influenza therapeutics.
Process Relevance
Antiviral Drug Screening
Application Stage
Hit-to-Lead Screening
Applications
Viral infection (influenza) and glycoprotein research.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 570 nm, or Fluorescence Detection (Ex 530 nm / Em 585 nm)
Sample Type
Serum, citrate-plasma, urine, cell lysate, culture medium
Research Areas
Virology (Influenza)
Size
100 tests
Data Output Type
Kinetic (Enzyme Activity)
Assay Time
Results in 60 min
LOD
OD 1 U/L; FL 0.01 U/L
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Neuraminidase cleaves sialic acid residues from cell surfaces. Influenza virus neuraminidase is essential for viral release; inhibitors like oseltamivir are standard antiviral therapeutics.