Short Description
Quantifies neuraminidase (sialidase) activity.
Development Stage
Research-Grade Protein & Enzyme Assay Development
Description
The ModifiSite™ Neuraminidase Assay Kit features a fluorometric substrate for the high-throughput screening of neuraminidase inhibitors, essential for influenza therapeutics. This assay validates the potency of antiviral drugs that block viral release from host cells. It supports virology research and the monitoring of drug resistance in influenza strains.
Features
Fluorometric substrate; High-throughput screening of neuraminidase inhibitors for influenza therapeutics.
Process Relevance
Antiviral Drug Screening
Application Stage
Hit-to-Lead Screening
Applications
Viral infection (influenza) and glycoprotein research.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 570 nm, or Fluorescence Detection (Ex 530 nm / Em 585 nm)
Sample Type
Serum, citrate-plasma, urine, cell lysate, culture medium
Research Areas
Virology (Influenza)