Development Stage: Research-Grade Protein & Enzyme Assay Development
Short Description
Measures plasmin activity in plasma or purified samples.
Brand
ModifiSite
Development Stage
Research-Grade Protein & Enzyme Assay Development
Description
The ModifiSite™ Plasmin Assay Kit uses a synthetic chromogenic substrate to validate fibrinolytic agents and antifibrinolytic drugs in hematology research. This assay supports the development of thrombolytic therapies by quantifying plasmin activity in plasma. It is a key tool for monitoring the regulation of the fibrinolytic system and assessing bleeding risks in pharmaceutical safety studies.
Features
Synthetic chromogenic substrate; Validates fibrinolytic agents and antifibrinolytic drugs in hematology.
Process Relevance
Thrombosis & Hemostasis Research
Application Stage
Pre-clinical Pharmacology
Applications
Fibrinolysis research and thrombolytic drug testing.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 405 nm
Sample Type
Serum and other biological samples
Research Areas
Hematology (Coagulation)
Size
100 tests
Data Output Type
Kinetic (Enzyme Activity)
Assay Time
Results in 30 min
LOD
0.35 U/L
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Plasmin is a serine protease that dissolves fibrin blood clots. Understanding plasmin function is critical for developing thrombolytic therapies for stroke and heart attack.