The kit is designed for in vitro quantitative measurement of Monkey CCL5 in Plasma, Serum, Tissue Homogenate.
Description
For quantitative detection of RANTES in serum, plasma, tissue homogenates.
Applications
ELISA
Target
CCL5
Reactivity
Monkey
Detection Method
Colorimetric
Method Type
Sandwich ELISA
Analytical Method
Quantitative
Sample Type
Plasma, Serum, Tissue Homogenate
Specificity
This assay has high sensitivity and excellent specificity for detection of RANTES. No significant cross- reactivity or interference between RANTES and analogues was observed. Note: Limited by current skills and knowledge, it is difficult for us to complete the cross-reactivity detection between RANTES and all the analogues, therefore, cross reaction may still exist.
Components
Pre-coated, ready to use 96-well strip plate Plate sealer for 96 wells Standard Sample/Standard Dilution Buffer Biotin-labeled Antibody (Concentrated) Antibody Dilution Buffer HRP-Streptavidin Conjugate (SABC) SABC Dilution Buffer TMB Substrate Stop Solution Wash Buffer (25 x concentrate) Instruction manual
Material not included
1.Microplate reader (wavelength:450nm) 2.37 °C incubator 3.Automated plate washer 4.Precision single and multi-channel pipette and disposable tips 5.Clean tubes 6.Deionized or distilled water
Sensitivity
18.75 pg/mL
Sample Volume
100 μL
Plate
Pre-coated
Reagent Preparation
Bring all reagents and samples to room temperature for 20 minutes before use. Wash Buffer Standards Preparation of Biotin-labeled Antibody Working Solution Preparation of HRP-Streptavidin Conjugate (SABC) Working Solution
Assay Procedure
Set standard, test samples (diluted at least 1/2 with Sample Dilution Buffer), control (blank) wells on the pre-coated plate respectively, and then, records their positions. Wash plate 2 times before adding standard, sample and control (blank) wells. Prepare Standards Add Samples Incubate Wash Biotin-labeled Antibody Wash HRP-Streptavidin Conjugate (SABC) Wash TMB Substrate Stop OD Measurement
Assay Precision
Intra-Assay: CV<8% Inter-Assay: CV<10%
Storage
4 °C,-20 °C
Storage Comment
1.For unopened kit: All the reagents should be kept according to the labels on vials. The Reference Standard, Biotin-labeled Antibody, HRP Conjugate and the 96-well stripe plate should be stored at -20 °C upon receipt while the other reagents should be stored at 4 °C. 2.For used kit: When the kit is used, the remaining reagents need to be stored according to the above storage condition. Besides, please return the unused wells to the foil pouch containing the desiccant pack, and zip-seal the foil pouch.
Expiry Date
6 months
Note
1.For unopened kit: All the reagents should be kept according to the labels on vials. The Reference Standard, Biotin-labeled Antibody, HRP Conjugate and the 96-well stripe plate should be stored at -20 °C upon receipt while the other reagents should be stored at 4 °C. 2.For used kit: When the kit is used, the remaining reagents need to be stored according to the above storage condition. Besides, please return the unused wells to the foil pouch containing the desiccant pack, and zip-seal the foil pouch.
Restrictions
For Research Use only
Alternative Name
Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES)
Rantes, Regulated On Activation, Normal T-Cell Expressed and Secreted, CCL5, SCYA5, SISd
UniProt
G7PU47
Pathways
Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
Protocol
1.Wash plate 2 times before adding Standard, Sample and Control wells! 2.Add 100 µL standard or sample to each well and incubate for 90 minutes at 37 °C. 3.Aspirate and wash plates 2 times. 4.Add 100 µL Biotin-labeled antibody working solution to each well and incubate for 60 minutes at 37 °C. 5.Aspirate and wash plates 3 times. 6.Add 100 µL SABC Working Solution into each well and incubate for 30 minutes at 37 °C. 7.Aspirate and wash plates 5 times. 8.Add 90 µL TMB Substrate Solution. Incubate 10-20 minutes at 37 °C. 9.Add 50 µL Stop Solution. Read at 450nm immediately and calculation.