mTOR-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR66
Cell Type: CD4⁺ T Cells
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: KMTs
RNA types: rRNA
Modification: ψ
RNA editing: A to I
Short Description
This product is a mTOR-targeted RNA modification and metabolomics analysis tool based on the ψ (METTL3-YTHDF1-FTO-KMTs-BHQ1) modification and Mevalonate pathway-mediated (FMRP-SAM-ADP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
KMTs
RNA types
rRNA
Modification
ψ
Label
BHQ1
RNA editing
A to I
Cell Type
CD4⁺ T Cells
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
rRNA-ψ-METTL3-YTHDF1-FTO-KMTs-BHQ1
Substrates
SAM
Cofactors
ADP
Pathway
Mevalonate pathway
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
FMRP
Metabolic Reprogramming
Mevalonate pathway-FMRP-SAM-ADP
Target
mTOR
Alternative Names
MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS; mechanistic target of rapamycin; mechanistic target of rapamycin kinase
Gene ID
2475(Human); 56717(Mouse); 56718(Rat)
UniProt ID
P42345(Human); Q9JLN9(Mouse); P42346(Rat)
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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