Creative Biolabs-Immuno-oncology

MTR-targeted RNA Modification and Metabolomics Analysis Tool (CAT#: ITS-0524-CR248)

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Short Description
This product is a MTR-targeted RNA modification and metabolomics analysis tool based on the ψ (METTL3-YTHDF1-FTO-ACOT12-phos) modification and Glycolysis-mediated (PRPF8-Lactyl-CoA-ADP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
ACOT12
RNA types
tRNA
Modification
ψ
Label
phos
RNA editing
A to I
Cell Type
M1 macrophages
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
tRNA-ψ-METTL3-YTHDF1-FTO-ACOT12-phos
Substrates
Lactyl-CoA
Cofactors
ADP
Pathway
Glycolysis
Epigenetic regulator
ACLY overexpression
Metabolic alteration
Increasing the content of acetyl-CoA
Targeting diseases
Adrenocortical carcinoma
RNA-binding proteins
PRPF8
Metabolic Reprogramming
Glycolysis-PRPF8-Lactyl-CoA-ADP
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For Research Use Only | Not For Clinical Use

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