MV-4-11 In Vitro Calcein AM Cytotoxic Assay (Cell Viability)

CAT#: ITS-1122-YF4312
Target Cell Organism: Human
Target Cell Alternative Name: MV(4;11)
Target Cell Name: MV-4-11
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide MV-4-11-based In Vitro Calcein AM Cytotoxic Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
MV-4-11
Target Cell Organism
Human
Target Cell Background
A model of human AML (acute myeloid leukemia) Acute myeloid leukemia (AML) is a malignant disorder of the progenitor cells in myeloid hematopoiesis and represents a genetically heterogeneous cancer.
Target Cell Alternative Name
MV(4;11)
Related Diseases
Acute Myeloid Leukemia; AML
Research Area
Oncology
Assay Name
In Vitro Calcein AM Cytotoxic Assay (Cell Viability)
Short Description
MV-4-11-cell based In Vitro Calcein AM Cytotoxic Assay (Cell Viability)
Assay Description
Calcein AM is another non-fluorescent cell permeable dye, which is converted to green-fluorescent calcein by viable intracellular esterases. Calcein violet AM, calcein red-orange, Oregon green 488 and 5-CFDA-AM are other examples of dyes used to monitor cell viability based on esterase activity in viable cells.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Viability Assay
Assay MOA
Cell-based Viability Assays Based on Cellular Enzymes and Proteins
For Research Use Only | Not For Clinical Use
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