NCI-H441 In Vivo Tumorigenesis Assay

This assay is to provide NCI-H441-based In Vivo Tumorigenesis Assay to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.

NCI-H441

Human

NCI-H441 [H441] cells were isolated in 1982 from the pericardial fluid of a male patient with papillary adenocarcinoma of the lung. Use these cells as a transfection host for expression of pulmonary surfactant protein (SP-B).

H441

Lung Cancer

Oncology

In Vivo Tumorigenesis Assay

Tumorigenicity is defined the property of a cell to form tumors when inoculated into an immunosuppressed animal model. Generally, test cells and tumor cells as positive control are administered subcutaneously into immunosuppressed nude mice. The number of animals developing tumors are compared with a positive control reference cell line.

Oncology In Vivo Assays