NCI-H446 In Vitro Ethidium Homodimer Assay (Cell Viability)

CAT#: ITS-0123-YF2122
Target Cell Organism: Human
Target Cell Alternative Name: H446
Target Cell Name: NCI-H446
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide NCI-H446-based In Vitro Ethidium Homodimer Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
NCI-H446
Target Cell Organism
Human
Target Cell Background
NCI-H446 [H446] cells were isolated in 1982 from the pleural fluid of a 61-year-old, White, male patient with small cell cancer of the lung.
Target Cell Alternative Name
H446
Related Diseases
Lung Cancer
Research Area
Oncology
Assay Name
In Vitro Ethidium Homodimer Assay (Cell Viability)
Assay Description
Ethidium homodimer assay is another cell viability assay, which can be used to detect dead cells. Ethidium homodimer can pene trate through the cell membrane and gives red fluorescence upon binding with DNA of dead cells.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Viability Assay
Assay MOA
Dye Exclusion Assays
For Research Use Only | Not For Clinical Use
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