OAA-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR327
Cell Type: M2 macrophages
RNA writers: NSUN6
RNA readers: YTHDF2
RNA erasers: TET1/2/3
Enzymes: ACSS2
RNA types: rRNA
Modification: ac4C
RNA editing: C to U
Short Description
This product is a OAA-targeted RNA modification and metabolomics analysis tool based on the ac4C (NSUN6-YTHDF2-TET1/2/3-ACSS2-phos) modification and Mevalonate pathway-mediated (hnRNPs-SAM-ATP) metabolic analysis system.
RNA writers
NSUN6
RNA readers
YTHDF2
RNA erasers
TET1/2/3
Enzymes
ACSS2
RNA types
rRNA
Modification
ac4C
Label
phos
RNA editing
C to U
Cell Type
M2 macrophages
Oligonucleotide
2'-H
RNA Construction
rRNA-ac4C-NSUN6-YTHDF2-TET1/2/3-ACSS2-phos
Substrates
SAM
Cofactors
ATP
Pathway
Mevalonate pathway
Epigenetic regulator
PKCλ/ι deficiency
Metabolic alteration
Favor the development of NEPC characteristics
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Mevalonate pathway-hnRNPs-SAM-ATP
Target
OAA
Alternative Names
Oxaloacetate; OAA
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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