OCFAs-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR355
Cell Type: M1 macrophages
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: D2HGDH
RNA types: mRNAs
Modification: m5C
RNA editing: G to A
Short Description
This product is a OCFAs-targeted RNA modification and metabolomics analysis tool based on the m5C (METTL3-YTHDF1-FTO-D2HGDH-spacer C9) modification and Fatty acid synthesis-mediated (MBNL-Succinyl-CoA-α-KG) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
D2HGDH
RNA types
mRNAs
Modification
m5C
Label
spacer C9
RNA editing
G to A
Cell Type
M1 macrophages
Oligonucleotide
PO, 2'-OMe, ENA
RNA Construction
mRNAs-m5C-METTL3-YTHDF1-FTO-D2HGDH-spacer C9
Substrates
Succinyl-CoA
Cofactors
α-KG
Pathway
Fatty acid synthesis
Epigenetic regulator
KDM5A overexpression
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Gastric Cancers
RNA-binding proteins
MBNL
Metabolic Reprogramming
Fatty acid synthesis-MBNL-Succinyl-CoA-α-KG
Target
OCFAs
Alternative Names
Odd-chain fatty acids; OCFAs
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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