OCI-Ly7 In Vitro ABTS Radical Cation Decolorization Assay (Oxidative Stress)

CAT#: ITS-0123-YF5013
Target Cell Organism: Human
Target Cell Name: OCI-Ly7
Assay Type: Oxidative Stress Assays
Assay Overview
This assay is to provide OCI-Ly7-based In Vitro ABTS Radical Cation Decolorization Assay (Oxidative Stress) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
OCI-Ly7
Target Cell Organism
Human
Target Cell Background
Human B-cell non-Hodgkin lymphoma cell line established from the peripheral blood sample of a 48-year-old man with B-cell non-Hodgkin lymphoma in 1984
Related Diseases
Lymphoma
Research Area
Oncology
Assay Name
In Vitro ABTS Radical Cation Decolorization Assay (Oxidative Stress)
Assay Description
It's a commonly used simple antioxidant assay. The ability of antioxidants to reduce ABTS free radical (ABTS.) to ABTS is measured in the ABTS assay.
Assay Type
Oxidative Stress Assays
Assay Type Details
Disturbance between the production of reactive oxygen species (ROS), free radicals and antioxidant mechanisms is defined as the oxidative stress, or more precisely, it is an imbalance between the oxidant and antioxidant state in cells. This imbalance can cause harmful effects to cells and biomolecules, which ultimately causes adverse effects in the whole organism. Oxidative imbalance can target important proteinsand lipids in cells, which can increase the risk of developing a cancer. On the other hand, increased ROS production in cancer cells by certain cancer drugs can also arrest cancer cell cycle and cause senescence and apoptosis through oxidative stress.
Assay Subtype
Antioxidant Assay
For Research Use Only | Not For Clinical Use
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