This assay is to provide OE33-based In Vivo Tumorigenesis Assay to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
OE33
Target Cell Organism
Human
Target Cell Background
The cell line OE33, also known as JROECL33, was established from the adenocarcinoma of the lower oesophagus (Barrett's metaplasia) of a 73 year old female patient. The tumour was identified as pathological stage IIA (UICC) and showed poor differentiation.
Target Cell Alternative Name
JROECL33
Related Diseases
Esophageal Adenocarcinoma
Research Area
Oncology
Assay Name
In Vivo Tumorigenesis Assay
Short Description
OE33-cell based In Vivo Tumorigenesis Assay
Assay Description
Tumorigenicity is defined the property of a cell to form tumors when inoculated into an immunosuppressed animal model. Generally, test cells and tumor cells as positive control are administered subcutaneously into immunosuppressed nude mice. The number of animals developing tumors are compared with a positive control reference cell line.