Obtain detailed visualization of ACE2 with this advanced IHC kit. It features a carefully balanced formulation designed to maximize signal intensity and specificity, enabling precise localization of the target protein.
Description
ACE2 (Angiotensin-converting enzyme 2), also called ACEH, is a zinc metalloprotease in the ACE family and a key regulator of the renin-angiotensin system. It is mainly expressed in the heart, kidneys, and testes, with low levels in various tissues. ACE2 is a functional receptor for SARS-CoV and SARS-CoV-2, influencing infection susceptibility, symptoms, and outcomes. It is a potential therapeutic target and localizes to the membrane and cytoplasm but accumulates in the nucleus during mitosis.
Features
Ready to use High Sensitivity Streptavidin (HSS) increases detection sensitivity Suitable for tissue sections & cytospin preparations Pre-diluted reagents minimize hands-on time Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Applications
IHC
Target
ACE2
Reactivity
Human, Mouse
Analytical Method
Immunohistochemistry
Sample Type
FFPE tissue
Components
Primary Antibody Secondary Antibody Antigen Unmasking Buffer Washing Buffer Blocking Buffer Color Development Reagent 1 Color Development Reagent 21 Signal Amplification Reagent Contrast Staining Agent Preservation Matrix
Storage
To ensure the preservation of their functional properties, all reagents within this kit must be maintained at a temperature between 2°C and 8°C. Under these storage conditions, the kit will retain its effectiveness for a period of 6 to 12 months following receipt.
Synonyms
ACE related carboxypeptidase; ACE2; ACEH; Angiotensin converting enzyme 2; Angiotensin I converting enzyme 2; Metalloprotease MPROT15
IHC Control Slides
Creative Biolabs control slides are prepared using top quality tissues that have been processed, embedded and sectioned following standard operating procedure. We provide the following antigen (tissue) controls: - Positive control: a section from a tissue known to express the protein of interest. - Negative control: a section from a tissue known not to express the target antigen. - Endogenous tissue background control: a section from the tissue that doesn't have a primary antibody applied.
Tissue Samples
Creative Biolabs also offers biospecimen including formalin fixed paraffin embedded (FFPE) tissue blocks, fresh or snap frozen tissue blocks, tissue microarray (TMA) slides. Please contact us to request a customized price quotation.
Tissue Processing Kit
Tissue Fixative Solution (Specified, depends on antigen type and tissue source) Tissue Processing Kit (Includes specialized media for tissue collection, isolation, and dissociation) Tissue Embedding Media Tissue Staining Kit (Optional)