Short Description
Visualize ADAR1 with clarity and confidence using this high-quality IHC kit. It features a comprehensive set of reagents and a user-friendly protocol, enabling researchers to achieve accurate and reproducible staining.
Description
ADAR1 (Adenosine deaminase acting on RNA 1), also known as DSRAD, G1P1, IFI4, converts specific adenosine residues into inosine in substrate RNAs with short dsRNA regions. The human ADAR1 gene encodes two RNA-specific adenosine deaminase isoforms: an IFN-inducible ~150 kDa protein and a constitutively expressed ~110 kDa protein. ADAR1 has five isoforms produced by alternative promoter usage and splicing. Defects in ADAR1 cause dyschromatosis symmetrica hereditaria (DSH). ADAR1 forms homodimers essential for its enzymatic activity.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry
Datasheet
