OncoIHC™ ADAR1 Ready-To-Use IHC Kit

Visualize ADAR1 with clarity and confidence using this high-quality IHC kit. It features a comprehensive set of reagents and a user-friendly protocol, enabling researchers to achieve accurate and reproducible staining.

ADAR1 (Adenosine deaminase acting on RNA 1), also known as DSRAD, G1P1, IFI4, converts specific adenosine residues into inosine in substrate RNAs with short dsRNA regions. The human ADAR1 gene encodes two RNA-specific adenosine deaminase isoforms: an IFN-inducible ~150 kDa protein and a constitutively expressed ~110 kDa protein. ADAR1 has five isoforms produced by alternative promoter usage and splicing. Defects in ADAR1 cause dyschromatosis symmetrica hereditaria (DSH). ADAR1 forms homodimers essential for its enzymatic activity.

Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining

IHC

ADAR1

Human, Mouse, Rat

Immunohistochemistry

FFPE tissue

Primary Antibody
Secondary Antibody
Antigen Unmasking Buffer
Washing Buffer
Blocking Buffer
Color Development Reagent 1
Color Development Reagent 29
Signal Amplification Reagent
Contrast Staining Agent
Preservation Matrix

To ensure the preservation of their functional properties, all reagents within this kit must be maintained at a temperature between 2°C and 8°C. Under these storage conditions, the kit will retain its effectiveness for a period of 6 to 12 months following receipt.

ADAR; ADAR1; DRADA; DSH; DSRAD; G1P1; IFI4; K88dsRBP; p136

Creative Biolabs control slides are prepared using top quality tissues that have been processed, embedded and sectioned following standard operating procedure. We provide the following antigen (tissue) controls:
- Positive control: a section from a tissue known to express the protein of interest.
- Negative control: a section from a tissue known not to express the target antigen.
- Endogenous tissue background control: a section from the tissue that doesn't have a primary antibody applied.

Creative Biolabs also offers biospecimen including formalin fixed paraffin embedded (FFPE) tissue blocks, fresh or snap frozen tissue blocks, tissue microarray (TMA) slides. Please contact us to request a customized price quotation.

Tissue Fixative Solution (Specified, depends on antigen type and tissue source)
Tissue Processing Kit (Includes specialized media for tissue collection, isolation, and dissociation)
Tissue Embedding Media
Tissue Staining Kit (Optional)