Short Description
This IHC kit offers a complete solution for Alpha Actinin staining, providing all necessary reagents in a convenient and ready-to-use format for a streamlined workflow and reliable results.
Description
Alpha catenins are crucial for linking E-cadherin-β-catenin complexes to the actin cytoskeleton in adherens junctions. Three isoforms exist, with varying tissue distribution. Alpha-E-catenin is present universally, Alpha-N is confined to neurons, and Alpha-T is found primarily in the heart. Reduced alpha-E-catenin levels are associated with various cancers and are linked to tumor differentiation and metastasis.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry