Short Description
Visualize Alpha Synuclein with precision using this high-quality IHC kit, which includes a comprehensive set of reagents designed to ensure optimal staining and accurate target detection.
Description
Alpha synuclein (α-syn) is a phosphoprotein localized at the presynaptic terminals of neurons, where it plays a crucial role in synaptic function and plasticity. It has gained significant attention due to its association with familial Parkinson's disease (PD) following the identification of the first α-syn mutation. The aggregation and hyperphosphorylation of α-syn are pathological hallmarks of Lewy body diseases, including Parkinson's disease, diffuse Lewy body disease, and the Lewy body variant of Alzheimer's disease.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry
Datasheet