OncoIHC™ CD147/BSG Ready-To-Use IHC Kit

CAT#: ITS-1122-ZP4805
Product Type: Kit
Target: CD147/BSG
Short Description
This IHC kit for CD147 offers a complete reagent set for straightforward staining from antigen retrieval through slide mounting.
Description
BSG, also named 5F7, Basigin, EMMPRIN, TCSF, and CD147, plays pivotal roles in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPs). CD147 may target monocarboxylate transporters SLC16A1, SLC16A3, and SLC16A8 to the plasma membranes of retinal pigment epithelium and neural retina. It appears to be a receptor for oligomannosidic glycans and mediates the degradation of the extracellular matrix, playing an important role in tumorigenesis and invasion in oral cancer. CD147 has been considered an objective and effective marker for predicting invasion and prognosis in various cancers.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Applications
IHC
Target
CD147/BSG
Reactivity
Human
Analytical Method
Immunohistochemistry
Sample Type
FFPE tissue
Components
Primary Antibody
Secondary Antibody
Antigen Unmasking Buffer
Washing Buffer
Blocking Buffer
Color Development Reagent 1
Color Development Reagent 116
Signal Amplification Reagent
Contrast Staining Agent
Preservation Matrix
Storage
To ensure the preservation of their functional properties, all reagents within this kit must be maintained at a temperature between 2°C and 8°C. Under these storage conditions, the kit will retain its effectiveness for a period of 6 to 12 months following receipt.
Synonyms
5F7; Basigin; basigin; BSG; CD147; Collagenase stimulatory factor; EMMPRIN; HAb18G; M6; OK blood group antigen; TCSF
IHC Control Slides
Creative Biolabs control slides are prepared using top quality tissues that have been processed, embedded and sectioned following standard operating procedure. We provide the following antigen (tissue) controls:
- Positive control: a section from a tissue known to express the protein of interest.
- Negative control: a section from a tissue known not to express the target antigen.
- Endogenous tissue background control: a section from the tissue that doesn't have a primary antibody applied.
Tissue Samples
Creative Biolabs also offers biospecimen including formalin fixed paraffin embedded (FFPE) tissue blocks, fresh or snap frozen tissue blocks, tissue microarray (TMA) slides. Please contact us to request a customized price quotation.
Tissue Processing Kit
Tissue Fixative Solution (Specified, depends on antigen type and tissue source)
Tissue Processing Kit (Includes specialized media for tissue collection, isolation, and dissociation)
Tissue Embedding Media
Tissue Staining Kit (Optional)
For Research Use Only | Not For Clinical Use
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