Make use of this complete, ready to use IHC kit, for CD206, to obtain optimal results. The kit contains every reagent required for the entire IHC process, beginning with antigen retrieval, and finalizing with coverslip mounting.
Description
CD206, also known as MMR, CLEC13D, and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 binds high-mannose structures on the surface of pathogens such as viruses, bacteria, and fungi, facilitating their neutralization by phagocytosis. It is a 170 kDa transmembrane protein containing 5 domains: cysteine-rich, fibronectin type II repeat, lectin-like carbohydrate recognition domains, transmembrane, and intracellular tail.
Features
Ready to use High Sensitivity Streptavidin (HSS) increases detection sensitivity Suitable for tissue sections & cytospin preparations Pre-diluted reagents minimize hands-on time Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Applications
IHC
Target
CD206
Reactivity
Human
Analytical Method
Immunohistochemistry
Sample Type
FFPE tissue
Components
Primary Antibody Secondary Antibody Antigen Unmasking Buffer Washing Buffer Blocking Buffer Color Development Reagent 1 Color Development Reagent 119 Signal Amplification Reagent Contrast Staining Agent Preservation Matrix
Storage
To ensure the preservation of their functional properties, all reagents within this kit must be maintained at a temperature between 2°C and 8°C. Under these storage conditions, the kit will retain its effectiveness for a period of 6 to 12 months following receipt.
Synonyms
CD206; CLEC13D; Macrophage mannose receptor 1; Mannose receptor; mannose receptor; C type 1; MMR; MRC1
IHC Control Slides
Creative Biolabs control slides are prepared using top quality tissues that have been processed, embedded and sectioned following standard operating procedure. We provide the following antigen (tissue) controls: - Positive control: a section from a tissue known to express the protein of interest. - Negative control: a section from a tissue known not to express the target antigen. - Endogenous tissue background control: a section from the tissue that doesn't have a primary antibody applied.
Tissue Samples
Creative Biolabs also offers biospecimen including formalin fixed paraffin embedded (FFPE) tissue blocks, fresh or snap frozen tissue blocks, tissue microarray (TMA) slides. Please contact us to request a customized price quotation.
Tissue Processing Kit
Tissue Fixative Solution (Specified, depends on antigen type and tissue source) Tissue Processing Kit (Includes specialized media for tissue collection, isolation, and dissociation) Tissue Embedding Media Tissue Staining Kit (Optional)