Short Description
For precise CYP2E1 staining, utilize this ready-to-deploy IHC solution, a comprehensive kit that simplifies procedures from antigen retrieval through coverslipping.
Description
CYP2E1, also known as CYPIIE1, 4-nitrophenol 2-hydroxylase, P450-J, and CYP2E, is a member of the cytochrome P450 family. It metabolizes several precarcinogens, drugs, and solvents into reactive metabolites. CYP2E1 inactivates certain drugs and bioactivates xenobiotics into hepatotoxic or carcinogenic forms. The enzyme catalyzes the conversion of 4-nitrophenol to 4-nitrocatechol, along with NADPH and oxygen, playing a crucial role in drug metabolism.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Analytical Method
Immunohistochemistry
Datasheet