Short Description
Enhance DACH1 staining efficiency using this pre-assembled IHC kit, supplying all necessary components for a seamless protocol.
Description
DACH1 is a key regulator of cell fate during development, particularly in the formation of the eye, leg, and brain in Drosophila. It interacts with coregulatory proteins like NCoR and Smad4 to inhibit TGF-beta signaling pathways. DACH1 also has tumor-suppressive properties, particularly in breast cancer, by controlling cyclin D1 expression. Additionally, DACH1 plays a role in regulating RANKL gene expression in osteoblast precursor cells and is involved in the progression of endometrial cancer.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry