OncoIHC™ DVL2 Ready-To-Use IHC Kit

Obtain rapid DVL2 staining with this fully prepared IHC solution, providing components for a streamlined workflow.

DVL2 is a member of the dishevelled (Dsh) protein family, encoding a 90-kD protein that undergoes phosphorylation to form a 95-kD cytoplasmic protein. DVL2 is involved in Wnt signaling by binding to the cytoplasmic C-terminus of Frizzled family receptors and transducing the signal to downstream effectors. It also mediates the internalization and degradation of Frizzled proteins during Wnt signaling. DVL2 contributes to both canonical and non-canonical Wnt signaling pathways and interacts with multiple Wnt genes.

Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining

IHC

DVL2

Human, Mouse

Immunohistochemistry

FFPE tissue

Primary Antibody
Secondary Antibody
Antigen Unmasking Buffer
Washing Buffer
Blocking Buffer
Color Development Reagent 1
Color Development Reagent 202
Signal Amplification Reagent
Contrast Staining Agent
Preservation Matrix

To ensure the preservation of their functional properties, all reagents within this kit must be maintained at a temperature between 2°C and 8°C. Under these storage conditions, the kit will retain its effectiveness for a period of 6 to 12 months following receipt.

Dishevelled 2; DSH homolog 2; DVL2

Creative Biolabs control slides are prepared using top quality tissues that have been processed, embedded and sectioned following standard operating procedure. We provide the following antigen (tissue) controls:
- Positive control: a section from a tissue known to express the protein of interest.
- Negative control: a section from a tissue known not to express the target antigen.
- Endogenous tissue background control: a section from the tissue that doesn't have a primary antibody applied.

Creative Biolabs also offers biospecimen including formalin fixed paraffin embedded (FFPE) tissue blocks, fresh or snap frozen tissue blocks, tissue microarray (TMA) slides. Please contact us to request a customized price quotation.

Tissue Fixative Solution (Specified, depends on antigen type and tissue source)
Tissue Processing Kit (Includes specialized media for tissue collection, isolation, and dissociation)
Tissue Embedding Media
Tissue Staining Kit (Optional)