Short Description
Facilitate EEF1A2 detection with this pre-prepared IHC kit, designed for a seamless antigen retrieval to coverslip procedure.
Description
eEF1A2, an isoform of eukaryotic elongation factor 1 alpha (eEF1A), shares over 90% sequence identity with eEF1A1. Besides its role in protein synthesis, eEF1A2 is involved in regulating the cell cycle, heat-shock response, aging, and posttranslational modifications. eEF1A2 is mainly expressed in tissues like the heart, brain, diaphragm, and skeletal muscle. It also promotes phospholipid signaling, Akt-dependent cell migration, and actin remodeling, which may drive tumorigenesis. eEF1A2 is linked to several cancers, including ovarian, prostate, pancreatic, breast, and lung cancers.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry