Creative Biolabs-Immuno-oncology

OncoIHC™ EIF3G Ready-To-Use IHC Kit (CAT#: ITS-1122-ZP4906)

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Short Description
Ensure consistent EIF3G staining with this pre-prepared IHC kit, supplying reagents tailored for efficient, start-to-finish staining.
Description
Eukaryotic translation initiation factor eIF3, which plays a central role in translation initiation, consists of five core subunits that are present in both budding yeast and higher eukaryotes. The EIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi, and eIF-5 to form the 43S preinitiation complex. The complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. It is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. EIF3G is a component of the EIF3 complex.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Applications
IHC
Target
EIF3G
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry
Sample Type
FFPE tissue

For Research Use Only | Not For Clinical Use

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