OncoIHC™ FOXO1 Ready-To-Use IHC Kit

CAT#: ITS-1122-ZP4928
Product Type: Kit
Target: FOXO1
Short Description
For precise FOXO1 staining, utilize this ready-to-deploy IHC solution, simplifying procedures from antigen retrieval through coverslipping.
Description
FOXO1 is a transcription factor that regulates cellular responses to oxidative stress and controls the cell cycle. It interacts with proteins like LRPPRC and SIRT1, influencing gene expression related to growth, quiescence, and stress responses. FOXO1 is involved in regulating glucose metabolism, aging, and the body's response to stress. Mutations in FOXO1 can cause diseases such as rhabdomyosarcoma, underlining its role in cancer and metabolism.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Applications
IHC
Target
FOXO1
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry
Sample Type
FFPE tissue
Components
Primary Antibody
Secondary Antibody
Antigen Unmasking Buffer
Washing Buffer
Blocking Buffer
Color Development Reagent 1
Color Development Reagent 239
Signal Amplification Reagent
Contrast Staining Agent
Preservation Matrix
Storage
To ensure the preservation of their functional properties, all reagents within this kit must be maintained at a temperature between 2°C and 8°C. Under these storage conditions, the kit will retain its effectiveness for a period of 6 to 12 months following receipt.
Synonyms
FKH1; FKHR; forkhead box O1; Forkhead box protein O1; Forkhead box protein O1A; Forkhead in rhabdomyosarcoma; FOXO1; FOXO1A
IHC Control Slides
Creative Biolabs control slides are prepared using top quality tissues that have been processed, embedded and sectioned following standard operating procedure. We provide the following antigen (tissue) controls:
- Positive control: a section from a tissue known to express the protein of interest.
- Negative control: a section from a tissue known not to express the target antigen.
- Endogenous tissue background control: a section from the tissue that doesn't have a primary antibody applied.
Tissue Samples
Creative Biolabs also offers biospecimen including formalin fixed paraffin embedded (FFPE) tissue blocks, fresh or snap frozen tissue blocks, tissue microarray (TMA) slides. Please contact us to request a customized price quotation.
Tissue Processing Kit
Tissue Fixative Solution (Specified, depends on antigen type and tissue source)
Tissue Processing Kit (Includes specialized media for tissue collection, isolation, and dissociation)
Tissue Embedding Media
Tissue Staining Kit (Optional)
For Research Use Only | Not For Clinical Use
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