OncoIHC™ Integrin alpha-1 Ready-To-Use IHC Kit

Ensure consistent Integrin alpha-1 staining with this pre-prepared IHC kit, supplying reagents tailored for efficient, start-to-finish staining.

Integrins are a large family of cell adhesion receptors that bind extracellular matrix ligands, cell-surface ligands, and soluble ligands. These transmembrane αβ heterodimers form at least 24 distinct combinations of 18 α-subunits and eight β-subunits. In addition to mediating cell adhesion, integrins are crucial for signaling pathways that regulate cellular processes such as migration, proliferation, differentiation, and apoptosis. Integrin alpha-1 (ITGA1, CD49a) pairs with beta-1 (ITGB1, CD29) to form a receptor that mediates cell adhesion to collagen and laminin, playing a role in inflammation and fibrosis.

Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining

IHC

Integrin

Human

Immunohistochemistry

FFPE tissue

Primary Antibody
Secondary Antibody
Antigen Unmasking Buffer
Washing Buffer
Blocking Buffer
Color Development Reagent 1
Color Development Reagent 328
Signal Amplification Reagent
Contrast Staining Agent
Preservation Matrix

To ensure the preservation of their functional properties, all reagents within this kit must be maintained at a temperature between 2°C and 8°C. Under these storage conditions, the kit will retain its effectiveness for a period of 6 to 12 months following receipt.

CD49a; Integrin alpha 1; ITGA1; Laminin and collagen receptor; VLA1

Creative Biolabs control slides are prepared using top quality tissues that have been processed, embedded and sectioned following standard operating procedure. We provide the following antigen (tissue) controls:
- Positive control: a section from a tissue known to express the protein of interest.
- Negative control: a section from a tissue known not to express the target antigen.
- Endogenous tissue background control: a section from the tissue that doesn't have a primary antibody applied.

Creative Biolabs also offers biospecimen including formalin fixed paraffin embedded (FFPE) tissue blocks, fresh or snap frozen tissue blocks, tissue microarray (TMA) slides. Please contact us to request a customized price quotation.

Tissue Fixative Solution (Specified, depends on antigen type and tissue source)
Tissue Processing Kit (Includes specialized media for tissue collection, isolation, and dissociation)
Tissue Embedding Media
Tissue Staining Kit (Optional)