OncoIHC™ JUP Ready-To-Use IHC Kit

CAT#: ITS-1122-ZP4701
Product Type: Kit
Target: JUP
Short Description
This IHC kit is specifically engineered for robust and reliable JUP staining. Its optimized formulation ensures consistent performance and minimizes variability, contributing to reproducible results.
Description
Plakoglobin (γ-catenin) is a member of the Armadillo protein family, involved in cell adhesion, Wnt signaling, and nuclear translocation to bind LEF1. It is a component of desmosomes and adherens junctions in cardiomyocytes. Mutations in plakoglobin are associated with arrhythmogenic right ventricular dysplasia and Pemphigus vulgaris.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Applications
IHC
Target
JUP
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry
Sample Type
FFPE tissue
Components
Primary Antibody
Secondary Antibody
Antigen Unmasking Buffer
Washing Buffer
Blocking Buffer
Color Development Reagent 1
Color Development Reagent 12
Signal Amplification Reagent
Contrast Staining Agent
Preservation Matrix
Storage
To ensure the preservation of their functional properties, all reagents within this kit must be maintained at a temperature between 2°C and 8°C. Under these storage conditions, the kit will retain its effectiveness for a period of 6 to 12 months following receipt.
Synonyms
ARVD12; Catenin gamma; CTNNG; Desmoplakin 3; Desmoplakin III; DP3; DPIII; junction plakoglobin; JUP; PDGB; PKGB; γ-Catenin
IHC Control Slides
Creative Biolabs control slides are prepared using top quality tissues that have been processed, embedded and sectioned following standard operating procedure. We provide the following antigen (tissue) controls:
- Positive control: a section from a tissue known to express the protein of interest.
- Negative control: a section from a tissue known not to express the target antigen.
- Endogenous tissue background control: a section from the tissue that doesn't have a primary antibody applied.
Tissue Samples
Creative Biolabs also offers biospecimen including formalin fixed paraffin embedded (FFPE) tissue blocks, fresh or snap frozen tissue blocks, tissue microarray (TMA) slides. Please contact us to request a customized price quotation.
Tissue Processing Kit
Tissue Fixative Solution (Specified, depends on antigen type and tissue source)
Tissue Processing Kit (Includes specialized media for tissue collection, isolation, and dissociation)
Tissue Embedding Media
Tissue Staining Kit (Optional)
For Research Use Only | Not For Clinical Use
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