OncoIHC™ PD-1 Ready-To-Use IHC Kit

CAT#: ITS-1122-ZP5136
Product Type: Kit
Target: PD-1
Short Description
This complete IHC kit for PD-1 offers a direct approach to staining, equipping users with reagents from antigen retrieval to slide mounting.
Description
Programmed Cell Death 1 (PD-1, also known as CD279) is an immunoinhibitory receptor involved in T-cell function regulation. Engagement with PD-L1 or PD-L2 inhibits T-cell proliferation and cytokine production. Blockade of PD-1 has antitumor activity and overcomes immune resistance.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Applications
IHC
Target
PD-1
Reactivity
Human
Analytical Method
Immunohistochemistry
Sample Type
FFPE tissue
Components
Primary Antibody
Secondary Antibody
Antigen Unmasking Buffer
Washing Buffer
Blocking Buffer
Color Development Reagent 1
Color Development Reagent 447
Signal Amplification Reagent
Contrast Staining Agent
Preservation Matrix
Storage
To ensure the preservation of their functional properties, all reagents within this kit must be maintained at a temperature between 2°C and 8°C. Under these storage conditions, the kit will retain its effectiveness for a period of 6 to 12 months following receipt.
Synonyms
CD279; hPD1; PD1; PD-1; PD-1/CD279; PDCD1; programmed cell death 1; SLEB2
IHC Control Slides
Creative Biolabs control slides are prepared using top quality tissues that have been processed, embedded and sectioned following standard operating procedure. We provide the following antigen (tissue) controls:
- Positive control: a section from a tissue known to express the protein of interest.
- Negative control: a section from a tissue known not to express the target antigen.
- Endogenous tissue background control: a section from the tissue that doesn't have a primary antibody applied.
Tissue Samples
Creative Biolabs also offers biospecimen including formalin fixed paraffin embedded (FFPE) tissue blocks, fresh or snap frozen tissue blocks, tissue microarray (TMA) slides. Please contact us to request a customized price quotation.
Tissue Processing Kit
Tissue Fixative Solution (Specified, depends on antigen type and tissue source)
Tissue Processing Kit (Includes specialized media for tissue collection, isolation, and dissociation)
Tissue Embedding Media
Tissue Staining Kit (Optional)
For Research Use Only | Not For Clinical Use
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