Short Description
Facilitate VIL1 detection with this ready-to-use IHC solution, streamlining procedures from antigen retrieval through slide preparation.
Description
Villin 1 (VIL1) is a severing protein expressed in epithelial cells with a brush border, such as in the intestinal mucosa, gall bladder, renal proximal tubules, and ductuli efferentes of the testis. VIL1 plays an important role in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration, and survival. It is also an anti-apoptotic protein and a diagnostic marker for various cancers, including cervical, endometrial adenocarcinomas, and renal cell carcinoma. VIL1 has been identified as a predictive biomarker for postoperative recurrence and poorer prognosis in high serum AFP-associated HCC.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Analytical Method
Immunohistochemistry
Datasheet
