Short Description
Measures G6P, the starting point of glycolysis.
Development Stage
Research-Grade Metabolic Assay Development
Description
The OXPHOSight™ Glucose-6-Phosphate Assay Kit analyzes the entry point of glucose into metabolic pathways, key for evaluating glycolytic inhibitors and pentose phosphate pathway modulators. This assay is essential for screening compounds that target the Warburg effect in cancer metabolism studies. By tracking this pivotal metabolite, researchers can assess the metabolic impact of new drugs on glucose utilization and cellular growth.
Features
Tracks the pivotal step in glycolysis and pentose phosphate pathways; Essential for screening glycolytic inhibitors in cancer metabolism (Warburg effect) studies.
Process Relevance
Glycolysis/Warburg Effect Research
Application Stage
Hit-to-Lead Screening
Applications
Essential for diabetes research and metabolic flux analysis.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 460 nm
Sample Type
Plasma, serum, tissue and culture media samples
Research Areas
Metabolic Disease; Oncology
Datasheet