OXPHOSight™ Glucose-6-Phosphate Dehydrogenase Kit

CAT#: ITS-1125-HM78
Product Type: Assay Kit
Species: All Species
Brand: OXPHOSight
Development Stage: Research-Grade Metabolic Assay Development
Short Description
Quantifies G6PDH activity via NADPH generation.
Brand
OXPHOSight
Development Stage
Research-Grade Metabolic Assay Development
Description
The OXPHOSight™ Glucose-6-Phosphate Dehydrogenase Kit is a homogeneous screening tool for identifying G6PD deficiency liabilities, crucial for the safety of antimalarial and oxidant drugs. This assay supports pharmacogenetic research by characterizing enzyme activity in patient samples. It is essential for pre-clinical safety assessments to prevent drug-induced hemolysis in susceptible populations.
Features
Homogeneous colorimetric assay; Screening for G6PD deficiency liabilities in antimalarial drug development.
Process Relevance
Pharmacogenetics (Hemolysis Risk)
Application Stage
Pre-clinical Safety
Applications
Screening for G6PD deficiency and hemolytic anemia risk.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 565 nm
Sample Type
Plasma, serum, tissue and culture media, samples
Research Areas
Hematology; Genetic Disorders
Size
100 tests
Data Output Type
Kinetic (Enzyme Activity)
Assay Time
Results in 20 min
LOD
0.2 U/L
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Glucose-6-Phosphate Dehydrogenase (G6PD) is the rate-limiting enzyme of the pentose phosphate pathway. Deficiency is a common genetic disorder predisposing red blood cells to hemolysis under oxidative stress.
For Research Use Only | Not For Clinical Use
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