Short Description
Determines GDH activity in serum or tissue.
Development Stage
Research-Grade Metabolic Assay Development
Description
The OXPHOSight™ Glutamate Dehydrogenase Assay Kit provides specific detection of GLDH, a sensitive biomarker for mitochondrial liver injury in toxicity assessments. This assay complements standard transaminase tests by indicating damage to the mitochondrial compartment of hepatocytes. It supports detailed hepatotoxicity mechanistic studies, helping to distinguish between cytosolic and mitochondrial damage.
Features
GLDH specific detection; Sensitive biomarker for mitochondrial liver injury in toxicity assessments.
Process Relevance
Mitochondrial Hepatotoxicity
Application Stage
Pre-clinical Safety
Applications
Liver specific injury marker assessment.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 565 nm
Sample Type
Serum, plasma, cell, tissue, agriculture samples
Research Areas
Hepatology; Toxicology
Datasheet