Short Description
Measures ketone bodies (acetoacetate and 3-hydroxybutyrate).
Development Stage
Research-Grade Metabolic Assay Development
Description
The OXPHOSight™ Ketone Body Assay Kit quantifies biomarkers of ketosis, facilitating the monitoring of diabetic ketoacidosis risk and the efficacy of ketogenic diet interventions. It precisely measures acetoacetate and 3-hydroxybutyrate, providing a complete picture of fatty acid breakdown. This assay is essential for metabolic clinical trials and for evaluating the safety and efficacy of drugs that influence ketone body production.
Features
Quantifies acetoacetate and 3-hydroxybutyrate; Monitors diabetic ketoacidosis risk and therapeutic ketosis in metabolic clinical trials.
Process Relevance
Diabetic Ketoacidosis Monitoring
Application Stage
Clinical Research
Applications
Monitoring fatty acid breakdown in diabetes and ketoacidosis.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 340 nm
Sample Type
Serum, plasma, urine samples
Research Areas
Diabetes & Obesity; Endocrinology