Short Description
Standard enzymatic assay for urea nitrogen (BUN).
Development Stage
Research-Grade Metabolic Assay Development
Description
The OXPHOSight™ Urea Assay Kit employs a urease-based reaction to determine blood urea nitrogen (BUN), the standard metric for renal clearance studies. This assay validates kidney function in toxicology models, helping to detect drug-induced nephropathy. It supports high-throughput screening of renal biomarkers, ensuring the safety of therapeutic candidates in pre-clinical development.
Features
Urease-based reaction; Standard BUN determination for renal clearance studies.
Process Relevance
Renal Clearance Studies
Application Stage
Pre-clinical Safety
Applications
Standard renal function test (BUN).
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 520 nm (Chemical)
Sample Type
Serum, plasma, urine, milk, cell/tissue culture, bronchoalveolar lavage (BAL), food, beverage, and environment
Research Areas
Nephrology; Toxicology
Datasheet