P450-Metric™ Cytochrome P450 17A1 (CYP17A1) ELISA Kit

CAT#: ITS-0326-YL3
Product Type: Assay Kit
Species: Mouse, Human
Brand: P450-Metric™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies CYP17A1 using a double-antibody sandwich ELISA.
Brand
P450-Metric™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
This meticulously optimized double-antibody sandwich ELISA kit offers highly accurate quantitative assessment of Cytochrome P450 17A1 expression within specialized research samples. Providing outstanding reproducibility and strict target specificity, this research-use-only immunoassay enables investigators to effectively explore complex steroidogenic metabolic pathways. It is an indispensable laboratory asset for evaluating the pharmacokinetics of targeted endocrine therapeutics and detecting off-target metabolic disruptions in preclinical ADME screening.
Features
This precise sandwich ELISA enables robust quantification of CYP17A1, supporting comprehensive preclinical investigations into steroidogenic pathways and targeted endocrine drug metabolism.
Process Relevance
Quantifying CYP17A1 to evaluate steroidal drug metabolism and screen for off-target endocrine disruptions.
Application Stage
Preclinical drug discovery, ADME profiling, and pharmacokinetic research
Applications
Quantify specific target enzyme levels in cell lysates, tissue homogenates, and biological fluids using this robust immunoassay.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Sample Type
Serum, plasma, tissue homogenates, cell lysates, other biological fluids
Research Areas
ADME; Endocrine Pharmacology; Drug Metabolism; Toxicology
Size
48 / 96 tests
Data Output Type
Absorbance (OD)
LOD
Mouse: 0.62 ng/mL
Human: 0.054 ng/mL
Species
Mouse, Human
Storage
Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Cytochrome P450 17A1 functions as a critical dual-activity enzyme in the steroidogenic pathway, mediating fundamental endocrine biosynthesis. Profiling its interaction with xenobiotics is essential for characterizing the metabolism of targeted endocrine drugs and identifying off-target hormonal disruptions.
For Research Use Only | Not For Clinical Use
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