P450-Metric™ Cytochrome P450 3A5 (CYP3A5) ELISA Kit

Quantifies CYP3A5 using a double-antibody sandwich ELISA.

P450-Metric™

ADME

Metabolism

This precision-engineered double-antibody sandwich ELISA kit provides exceptionally accurate quantitative measurement of Cytochrome P450 3A5 in diverse laboratory samples. Delivering strict target specificity and robust reproducibility, this research-use-only platform allows researchers to investigate highly polymorphic hepatic drug metabolism extensively. It is an indispensable analytical instrument for predicting inter-individual variability in xenobiotic clearance and identifying severe drug-drug interactions during early-stage preclinical pharmacokinetic and ADME profiling.

This exceptionally sensitive sandwich ELISA enables precise quantification of CYP3A5, facilitating critical evaluation of polymorphic drug metabolism and predicting inter-individual variability in drug clearance.

Quantifying CYP3A5 to predict individual variations in drug clearance and navigate specific drug-drug interactions.

Preclinical drug discovery, ADME profiling, and pharmacokinetic research

Evaluate target protein levels across tissue homogenates and cell lysates with this specific quantitative sandwich ELISA.

Internal performance validation using reference standards under defined assay conditions.

Serum, plasma, tissue homogenates, cell lysates

ADME; Pharmacogenomics; Drug Metabolism; Pharmacokinetics

48 / 96 tests

Absorbance (OD)

Rat: 0.59 ng/mL

Rat

Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.

Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.

For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.

For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.

Shipped on ice under temperature-controlled conditions.

As a prominent polymorphic member of the CYP3A subfamily, Cytochrome P450 3A5 significantly contributes to the oxidative metabolism of numerous pharmaceuticals. Its evaluation is indispensable in ADME studies for modeling polymorphic metabolic clearance and predicting inter-individual variability in drug efficacy.