PDC-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR365
Cell Type: M1 macrophages
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: HDACs
RNA types: mRNAs
Modification: m6A
RNA editing: C to U
Short Description
This product is a PDC-targeted RNA modification and metabolomics analysis tool based on the m6A (METTL3-YTHDF1-FTO-HDACs-Hexynyl) modification and Fatty acid synthesis-mediated (RBM9-Acetyl-CoA-ADP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
HDACs
RNA types
mRNAs
Modification
m6A
Label
Hexynyl
RNA editing
C to U
Cell Type
M1 macrophages
Oligonucleotide
PO, 2'-OMe, ENA
RNA Construction
mRNAs-m6A-METTL3-YTHDF1-FTO-HDACs-Hexynyl
Substrates
Acetyl-CoA
Cofactors
ADP
Pathway
Fatty acid synthesis
Epigenetic regulator
SMARCA4 deficiency
Metabolic alteration
Upregulating oxidative phosphorylation
Targeting diseases
Nasopharyngeal carcinoma
RNA-binding proteins
RBM9
Metabolic Reprogramming
Fatty acid synthesis-RBM9-Acetyl-CoA-ADP
Target
PDC
Alternative Names
Pyruvate dehydrogenase complex; PDC
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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