PGK 1-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR32
Cell Type: M1 macrophages
RNA writers: METTL3
RNA readers: YTHDC1
RNA erasers: ALKBH5
Enzymes: FDH
RNA types: mRNAs
Modification: m6Am
RNA editing: C to U
Short Description
This product is a PGK 1-targeted RNA modification and metabolomics analysis tool based on the m6Am (METTL3-YTHDC1-ALKBH5-FDH-spacer C18) modification and Mevalonate pathway-mediated (hnRNPs-Lactyl-CoA-ADP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDC1
RNA erasers
ALKBH5
Enzymes
FDH
RNA types
mRNAs
Modification
m6Am
Label
spacer C18
RNA editing
C to U
Cell Type
M1 macrophages
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-m6Am-METTL3-YTHDC1-ALKBH5-FDH-spacer C18
Substrates
Lactyl-CoA
Cofactors
ADP
Pathway
Mevalonate pathway
Epigenetic regulator
G9A overexpression
Metabolic alteration
Upregulating serine-glycine biosyntheticpathway
Targeting diseases
Adrenocortical carcinoma
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Mevalonate pathway-hnRNPs-Lactyl-CoA-ADP
Target
PGK 1
Alternative Names
PGK 1; Phosphoglycerate kinase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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