Short Description
This product is a PPIA-targeted RNA modification and metabolomics analysis tool based on the m6Am (METTL14-YTHDF2-ALKBH5-ALKBH5-spacer C9) modification and TCA cycle-mediated (NUDT21-Acetyl-CoA-ADP) metabolic analysis system.
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-m6Am-METTL14-YTHDF2-ALKBH5-ALKBH5-spacer C9
Epigenetic regulator
SIRT6 deficiency
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
NUDT21
Metabolic Reprogramming
TCA cycle-NUDT21-Acetyl-CoA-ADP