Precorrin-8X Methylmutase-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR291
Cell Type: DCs
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: LDH
RNA types: rRNA
Modification: ac4C
RNA editing: G to A
Short Description
This product is a Precorrin-8X methylmutase-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL14-YTHDF2-ALKBH5-LDH-BHQ1) modification and Glycolysis-mediated (FMRP-Succinyl-CoA-α-KG) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
LDH
RNA types
rRNA
Modification
ac4C
Label
BHQ1
RNA editing
G to A
Cell Type
DCs
Oligonucleotide
2'-MOE
RNA Construction
rRNA-ac4C-METTL14-YTHDF2-ALKBH5-LDH-BHQ1
Substrates
Succinyl-CoA
Cofactors
α-KG
Pathway
Glycolysis
Epigenetic regulator
SETD2 deficiency
Metabolic alteration
Upregulating oxidative phosphorylation andfatty acid synthesis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
FMRP
Metabolic Reprogramming
Glycolysis-FMRP-Succinyl-CoA-α-KG
Target
Precorrin-8X methylmutase
Alternative Names
Precorrin-8X methylmutase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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