RANK (Human) Activator/Inhibitor Screening Assay, HEK293 (RANK & NF-κB)-based

This assay is used to screen for inhibitors of RANKL/RANK signaling in a cellular context. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.

Customized to client's specific requirements

HEK293

Human

Creative Biolabs has developed several immune checkpoint stable cell Lines expressing the most popular immune checkpoints to accelerate clients' immunotherapy discovery and clinical translation. Recombinant HEK-293 cells expressing firefly luciferase gene under the control of Nuclear factor-κB (NF-κB) with constitutive expression of human RANK (Receptor activator of nuclear factor-κB; TNFRSF11A; ref. seq. NM_003839.2). Which can be used in binding assays and functional assay.

HEK293 (RANK & NF-κB)

Cancer

Oncology

In Vitro Activator/Inhibitor Screening Assay

Screen for inhibitors of RANKL/RANK signaling in a cellular context.

Creative Biolabs has developed several I-O function assay based on our stable cell Lines expressed the most popular immune checkpoints. RANK (Human) Activator/Inhibitor Screening Assay, HEK293 (RANK & NF-κB)-based is applied to screen for inhibitors of RANKL/RANK signaling in a cellular context. The assay will be customized according to the client's specific requirements. Please contact our scientists to discuss more details.

In Vitro Activator/Inhibitor Screening Assay; Activator/Inhibitor Screening Assay

NF-κB Reporter

Activator/Inhibitor Screening Assay

Creative Biolabs has developed several immune checkpoint stable cell Lines expressing the most popular immune checkpoints to accelerate clients' immunotherapy discovery and clinical translation. Recombinant HEK-293 cells expressing firefly luciferase gene under the control of Nuclear factor-κB (NF-κB) with constitutive expression of human RANK (Receptor activator of nuclear factor-κB; TNFRSF11A; ref. seq. NM_003839.2). Which can be used in binding assays and functional assay.