Alternative Name
Interferon gamma
Synonyms
IFG; IFI; IFN-g; Ifg; IFNG2; IFN-gamma; IFN-G; IFNG; IFNgamma; TCRalpha; INF-G; ifng; interferon gamma; interferon; gamma 1-2; IFNG; Ifng; ifng1-2
Background
Interferon gamma (IFN-γ) is a multifunctional protein first observed as an antiviral activity in cultures of Sindbis virus-infected human leukocytes stimulated by PHA (1). Produced by Tlymphocytes and natural killer (NK) cells, IFN-γis now known to be both an inhibitor of viral replication and a regulator of numerous immunological functions.
Pathways
Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
Datasheet