Rpi-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR116
Cell Type: MDSCs
RNA writers: METTL3
RNA readers: YTHDC1
RNA erasers: ALKBH5
Enzymes: KMTs
RNA types: rRNA
Modification: ac4C
RNA editing: A to I
Short Description
This product is a Rpi-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL3-YTHDC1-ALKBH5-KMTs-phos) modification and Mevalonate pathway-mediated (ATAXIN-2-SAM-NAD+) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDC1
RNA erasers
ALKBH5
Enzymes
KMTs
RNA types
rRNA
Modification
ac4C
Label
phos
RNA editing
A to I
Cell Type
MDSCs
Oligonucleotide
cET, 2'-MOE
RNA Construction
rRNA-ac4C-METTL3-YTHDC1-ALKBH5-KMTs-phos
Substrates
SAM
Cofactors
NAD+
Pathway
Mevalonate pathway
Epigenetic regulator
P300/CBP overexpression
Metabolic alteration
Upregulating glycolysis and amino acidsmetabolism
Targeting diseases
Prostate Cancers
RNA-binding proteins
ATAXIN-2
Metabolic Reprogramming
Mevalonate pathway-ATAXIN-2-SAM-NAD+
Target
Rpi
Alternative Names
Ribose-5-phosphate isomerase; Rpi
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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