SU-DHL-8 In Vitro Telomere Length Analysis Assay (Senescence)
CAT#: ITS-0123-YF5611
Target Cell Organism: Human
Target Cell Name: SU-DHL-8
Assay Type: Cellular Senescence in Cancer Assays
Assay Overview
This assay is to provide SU-DHL-8-based In Vitro Telomere Length Analysis Assay (Senescence) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
SU-DHL-8
Target Cell Organism
Human
Related Diseases
Large Cell Lymphoma
Research Area
Oncology
Assay Name
In Vitro Telomere Length Analysis Assay (Senescence)
Assay Description
For the analysis of telomere length, terminal restriction fragment anal ysis technique has been the commonly used technique for a long time.
Assay Type
Cellular Senescence in Cancer Assays
Assay Type Details
Cell senescence is described as an irreversible physiological event of cell growth arrest, which is known to be caused by alterations of telomeres, oxidative stress, DNA damage and some oncogenes. Inhibition of the program of senescence is one of the main features of tumor cells and it has been reported that cancer cells can be induced to undergo senescence by chemo- and radiotherapies and genetic alterations. Telomeres help to prevent uncontrolled cell proliferation and the absence of telomeres results in aneuploidy and cell death.